Dinner

Leftover Turkey Noodle Casserole Recipe

BySimon Carel January 12, 2026January 12, 2026

Introduction

This Leftover Turkey Noodle Casserole is a comforting and easy way to transform your Thanksgiving turkey into a delicious, hearty meal. Packed with creamy sauce, tender noodles, and melted cheese, it’s perfect for using up leftovers and feeding the whole family.

The image shows a pale blue casserole dish filled with creamy chicken and vegetable pasta. The dish has several visible layers: at the bottom is a soft layer of cooked pasta shells mixed with diced carrots and green peas, covered by a thick, white, creamy sauce mixed with chunks of chicken and scattered vegetables, giving the dish a rich and smooth texture. A silver spoon held by a woman's hand is lifting a scoop of the pasta, showing the saucy, cheesy surface on top and the mixed ingredients underneath. The background features a white marbled surface, adding a clean and bright look to the setting. Photo taken with an iphone --ar 4:5 --v 7

Ingredients

4 cups (8 oz.) uncooked egg noodles
3 cups chopped leftover cooked turkey
1 (12 oz.) package frozen mixed vegetables, thawed and warmed
1 (10.5 oz.) can condensed cream of chicken soup
1 cup sour cream
1/3 cup milk
1 1/4 teaspoons dried thyme
1/2 teaspoon dried sage
3/4 teaspoon salt
1/2 teaspoon pepper
1/4 cup shredded or grated Parmesan cheese
1 1/2 cups shredded mozzarella cheese, divided

Instructions

Step 1: Cook the egg noodles in salted boiling water according to the package directions. Drain them well and set aside.
Step 2: In a large mixing bowl, combine the condensed cream of chicken soup, sour cream, milk, dried thyme, dried sage, salt, pepper, Parmesan cheese, and 1 cup of shredded mozzarella. Stir until well mixed.
Step 3: Add the chopped leftover turkey and warmed mixed vegetables to the sauce mixture. Stir to combine.
Step 4: Stir the hot drained noodles into the mixture until everything is evenly coated.
Step 5: Grease a 2-quart baking dish and spoon the noodle mixture into it. Sprinkle the remaining 1/2 cup shredded mozzarella evenly over the top.
Step 6: Bake at 350℉ (175℃) for 25 to 30 minutes, until the casserole is heated through and the cheese is melted and bubbly.

Tips & Variations

Use fresh or frozen vegetables of your choice if you prefer something other than mixed veggies.
For extra crunch, top the casserole with breadcrumbs mixed with melted butter before baking.
Swap the cream of chicken soup for cream of mushroom for a different flavor profile.
Add a handful of chopped fresh parsley or green onions for a pop of color and freshness.
If you don’t have leftover turkey, cooked chicken works equally well in this recipe.

Storage

Store any leftover casserole in an airtight container in the refrigerator for up to 3 days. To reheat, cover with foil and warm in a 350℉ oven until heated through, about 15-20 minutes. You can also microwave individual portions until hot.

How to Serve

A white plate with a light blue patterned rim holds a creamy pasta dish with spiral noodles covered in melted white cheese. Mixed into the pasta are small pieces of red and green bell peppers and light green herbs, giving a colorful contrast. The cheese on top is gooey and thick, slightly browned in spots, and the noodles underneath appear soft and coated in a creamy sauce. The plate sits on a white marbled surface, and a spoon is visible near the edge of the frame. photo taken with an iphone --ar 4:5 --v 7

Serve this delicious recipe with your favorite sides.

FAQs

Can I make this casserole ahead of time?

Yes, you can assemble the casserole a day in advance and refrigerate it uncovered. When ready to bake, add a few extra minutes to the baking time since it will be cold.

Can I freeze the leftover turkey noodle casserole?

This casserole can be frozen before baking. Cover tightly with foil and freeze for up to 2 months. Thaw overnight in the refrigerator before baking as directed.